Therefore, to investigate the effect of gAcrp on cancer cell inflammasomes, we first examined the effect of gAcrp on the maturation of IL-1β and observed that gAcrp substantially decreased the level of active IL-1β in MCF-7 breast cancer cells in a time- and dose-dependent manner without significant effect on pro-IL-1β expression (Figure 1A,B). This evidence concerns the gene IL1B and breast cancer.