AKT1 and malignant colon neoplasm: In the present study, we found that the AMTs 1, 2, 3, 4, 7, and 8 reduce the protein levels of p-AKT in HT-29 cells, indicating the role of these AMTs in the downregulation of proliferation, cell cycle, apoptosis, and metastasis in colon cancer cells through the regulation of MAPK and AKT pathways.