Global profiling methylation data were also compared to 32 samples randomly extracted from internal and external datasets [21] among those classifying as central nervous system neuroblastoma FOXR2 (CNS-NB-FOXR2), CIC rearranged sarcoma (EFT-CIC), high-grade neuroepithelial tumor MN1 (HGNET-MN1), and high-grade neuroepithelial tumor BCOR (HGNET-BCOR) using the Heidelberg brain tumor and sarcoma classifier. This evidence concerns the gene FOXR2 and brain neoplasm.