Seventeen variants were reported in genes that had been previously associated with hypospadias (ATF3, BNC2, CYP1A1, EMX2, EYA1, FLNA, GLI3, GRID1, GLI2, BNC2, FGF10, HOXA13, HSD3B2, IRX5, IRX6, PPARGC1B, and WDR11), eight with cryptorchidism (BNC2, FLNA, RET, RECQL4, NRP1, PTPN11, RIPK4, and ZBTB16), and five with micropenis (ZBTB16, BNC2, EVC, FGF10, and RIPK4). This evidence concerns the gene RIPK4 and hypospadias.