CLDN16 and Hypercalciuria: Interestingly, a heterozygous variant of SLC34A3 (c.589A>G) was found in the patient and his symptomatic father by the reanalysis of the trio WES data, especially for the causes of idiopathic hypercalciuria, including CLCN5, CASR, CLDN16, CLDN19, ADCY10, SLC9A3R1, GLUT2, HSPG2, FN1, CYP24A1, SLC34A1, and SLC34A3 (Dasgupta et al., 2014; Stechman, Loh, & Thakker, 2009).