The RCN expansions of (CGG)n in 5′UTRs of the fragile X mental retardation-1 (FMR1) gene were n ≥ 200, which resulted in human mental retardation [44], whereas the (CGG)40–200 were also related to cognitive/psychosocial impairment [45], fragile-X-like phenotypes, and woman ovarian dysfunction [46, 47]. Here, FMR1 is linked to ovarian dysfunction.