Programmed cell death‐ligand 1 (PD‐L1), which is widely expressed in immune cells, lymphatic endothelial cells, blood endothelial cells, tumor cells and so on, can suppress immune‐response.14, 15 High expression of PD‐L1 is associated with an unfavorable survival in patients with lung cancer.16 This evidence concerns the gene CD274 and lung cancer.