Recently, it has been reported that the activation of FGF19-FGFR4 signaling is closely associated with cancer development and progression (Zhang et al., 2011; Chen et al., 2019), suggesting that FGF19-FGFR4 might be an attractive target for effective anticancer therapeutics (Schadt et al., 2018; Gao et al., 2019). This evidence concerns the gene FGF19 and cancer.