The lower phosphorylation levels in the BP cells suggests that CREB may be regulating cell cycle progression in the MS cells yet not the BP cells; however, this could mean that CREB may be inactivated temporarily in the BP cells yet when these cells are allowed to recuperate from the bioprinting process, CREB levels may rise again to levels typical of cancer cells. The gene discussed is CREB1; the disease is myeloid sarcoma.