Several lncRNAs, including HOTAIR, H19, MALT1, CCAT2, SPRY4-IT1, GAS5, CCHE1, MEG3, LET, EBIC, and PVT1, are recognized to play crucial functions in cervical cancer progression, invasion and metastasis as well as in radio-resistance [Table 2; (29, 165)]. The gene discussed is SPRY4; the disease is cervical cancer.