DiR+ MM cells in the calvarium vasculature (the central vessel, parasagittal sinusoids, and the lateral region) and the bone marrow space were measured at 2 h after cell injection using confocal microscopy as previously described (Figure4A).16 Overexpression of PINK1 demonstrated a trend to suppress myeloma cell homing/migration to the calvarium at 2 h after cell injection (Figure 4A‐a,b), which was attenuated by a PINK1‐specific shRNA (Figure 4A‐c) (the full images are included in Figures S8–S10 and the video recordings are provided in Videos S11–S13 in the Supporting Information). This evidence concerns the gene PINK1 and plasma cell myeloma.