To this end, we used three different approaches to induce PINK1‐dependent mitophagy (treatment with carbonylcyanide‐m‐chlorophenylhydrazone (CCCP), salinomycin, or overexpression of PINK1), and then examined the effects of increased mitophagy on myeloma cell proliferation, survival, and migration in vitro. The gene discussed is PINK1; the disease is plasma cell myeloma.