The levels of log HOMA2-IR (P = 0.030), HOMA2-IS (P = 0.021), SBP (P = 0.003), IL-6 (P = 0.049), and adiponectin (P = 0.032) were statistically different between AA with and without T2D, but these differences were not observed among the HA ethnic subgroup. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.