PLAC1 protein is mainly expressed in placenta 9–12, while it is frequently activated in a variety of cancers including cancers of breast 13–16, lung 13–15,17,18, liver 14,17,19, colon 14,15,17,20–22, stomach 13,23,24, ovary 13,25,26, uterus 27,28, cervix 14,29, pancreas 30, and prostate 31,32. The gene discussed is PLAC1; the disease is cancer.