The network revealed that CRC-related DERs such as hsa-miR-1-3p, hsa-miR-490-3p, hsa-miR-542-5p, hsa-miR-424-5p, and hsa-miR-133a-3p are associated with the regulation of several cancer-related pathways by targeting TIMP3, FOS, PPP1R12B, CCND2, and EGFR. The gene discussed is EGFR; the disease is colorectal carcinoma.