PfEMP1 has been found to bind to CD36 on platelets via CIDRα2-6 domains in uncomplicated/mild malaria (UM/MM) (Mkumbaye et al., 2017; Mustaffa et al., 2017), and to ICAM-1 on endothelial cells in severe malaria (SM) via DBLβ5 domains (Mustaffa et al., 2017; Tuikue Ndam et al., 2017). This evidence concerns the gene ICAM1 and malaria.