DTL and hepatocellular carcinoma: It has been reported that DTL plays an essential role in cell proliferation, cell cycle arrest and metastatic potential in hepatocellular carcinoma, breast cancer, gastric cancer and rhabdomyosarcoma (Pan et al., 2006; Ueki et al., 2008; Li et al., 2009; Missiaglia et al., 2009; Song et al., 2010).