Since MDSCs are abundant in tumor and play important roles in tumor progression (13), we then investigated whether LCN2 expression in M-MDSC (CD11b+Ly6GlowLy6Chi) and PMN-MDSC (CD11b+Ly6GhiLy6Clow) were changed in the tumor after stroke. The gene discussed is ITGAM; the disease is neoplasm.