APOE and atherosclerosis: Although the colonization of live A. muciniphila did not result in the alteration of serum total cholesterol (TC), total triglyceride (TG), high density lipoprotein (HLD), and LDL in Apoe–/– mice, the soluble receptor for tumor necrosis factor type II (sTNFRII) was significantly reduced, which led to improvement in atherosclerosis and congestive heart failure (Li et al., 2016).