For example, miR-200b and miR-429 suppress the expression of zinc finger E-box binding homeobox 1 (ZEB1) and zinc finger E-box binding homeobox 2 (ZEB2), the two cellular proteins that have key roles to establish and maintain latent infections of Epstein–Barr virus, thus leading to lytic reactivation of latently infected cells (Ellis-Connell et al., 2010). Here, ZEB1 is linked to disease arising from reactivation of latent virus.