Compared to those without hyperuricemia [HU (–)], postmenopausal women with hyperuricemia [HU (+)] were older and had a significantly greater BMI; lower levels of HDL and eGFR; higher levels of TG, TT, FSH, LH, and DHEA; and a higher prevalence of hypertension and dyslipidemia (P < 0.05). Here, PLOD1 is linked to hyperuricemia.