TGFB1 and diabetes mellitus: Impaired cardiac function in terms of LV diastolic dysfunction is associated with interstitial fibrosis and pathological cardiomyocyte hypertrophy in animal models of diabetes (Huynh et al., 2014; Marwick et al., 2018), a pathological adaption to diabetes that is linked to increased expression of pro-fibrotic Tgf-β (Mizushige et al., 2000).