NLRP3 and inflammatory response: Data from Crataegus aronia extracts showed inhibition of the nuclear accumulation of NF-κB and NLRP-3 protein levels and caspase-1 in HFD-induced aortic vascular inflammation in rats, thus suggesting inhibition of the NLRP3 inflammasome-mediated pathway (Shatoor and Al Humayed, 2019).