Interestingly, resolution of neuropathic pain in mouse models of chemotherapy-induced neuropathy requires CD8+ T cells (Krukowski et al., 2016; Laumet et al., 2019a); in these studies the authors propose an indirect involvement of CD8+ T cells in suppressing DRG neuron activity by upregulation of IL-10 signaling (Krukowski et al., 2016). This evidence concerns the gene CD8A and neuropathy.