The tumor suppressor function of CAV1 in the presence of E-cadherin is associated with the formation of a multiprotein complex that recruits β-catenin to the plasma membrane [10], thereby decreasing β-catenin/Tcf-Lef dependent expression of the protein survivin and cyclooxygenase-2, which promote cell survival [11, 12]. This evidence concerns the gene CAV1 and neoplasm.