CXCR1 is one of the major chemokine receptors on polymorphionuclear neutrophils [23], and the involvement of polymorphionuclear neutrophils in sepsis is well recognized [24–27].CLEC4D, a member of Dectin-2 family, functions in resolution of inflammation, possibly through facilitating neutrophil turnover [28]. This evidence concerns the gene CLEC4D and Sepsis.