Correlation analysis between serum α-synuclein and disease severity revealed that the number of antiepileptic medications and the duration of last seizure before the blood collection were correlated with serum α-synuclein and IL-6 levels in patients with epilepsy (Table 5 and Fig. 1 (B) & 3 (C); p < 0.05, r = 0.2132 and p < 0.05, r = 0.1884). The gene discussed is IL6; the disease is epilepsy.