In addition, many other genes were also found to be regulated by epigenetic factors and related to liver disease, such as MARCH1 [50,51], LIMD2 [52], SLC39A8 [52], etc. Meanwhile, some genes have not been proved to be included in the process of fatty liver or other liver disease, such as ASPA, CCDC18, etc. Which provided new targets for the epigenetic study of fatty liver. The gene discussed is CCDC18; the disease is liver disorder.