To determine whether HSP90 is a direct target of miR-361, the pGL3 luciferase reporter vector containing the WT HSP90 3′-UTR or the MUT HSP90 3′-UTR were transfected into cervical cancer cells, together with miR-361 mimic, miR-361 inhibitor, or the respective negative controls, respectively. Here, HSP90AB1 is linked to cervical carcinoma.