GLS and neoplasm: Increased GLS-1 expression was detected in SDHB-mutant tumor tissues compared to RET-mutant and sporadic tumors, however the difference was not significant (H-score: 87.8 ± 64 vs. 59 ± 82.4 SDHB-mutant vs. RET-mutant, p = 0.22; H-score: 87.8 ± 26 vs. 53.6 ± 47.8, SDHB-mutant versus sporadic, p = 0.15).