ABCB1 and osteosarcoma: Moreover, EVs carrying the P-glycoprotein (P-gp, also called MDR-1 or ABCB1) drug efflux pump mediated the transfer of multidrug resistance to sensitive cells in many human cancer models, including prostate and ovarian cancers, acute T lymphoblastic leukemia, and osteosarcoma [169,171,172,173].