Our previous study found MDV could reverse the ubiquitylome of chicken T-cell lymphoma by comparison with normal CD4+ T cells, and the N-terminal 75 kDa fragment of UL36, which contains the viral DUB catalytic domain (UL36-DUB), exists in MDV-induced T lymphoma cells in high level [28]. Here, ZUP1 is linked to T-cell non-Hodgkin lymphoma.