Ectopic expression of miR-18a is capable of retarding gastric tumor growth and angiogenesis through the inhibition of mTOR pathway and is inversely correlated with PIAS3 expression, a STAT3 inhibitor, leading to STAT3p upregulation and induction of MYC expression, with a high predictive value for prognosis of patients with GC [89,138,139]. Here, MYC is linked to gastric neoplasm.