IGF1 and melanoma: For rs1520220/IGF1 in the recessive model, men with GG genotype showed extremely high risk of melanoma (OR 8.11, 95% CI: 2.20, 52.50, p = 0.006) while women with GG genotype showed a significant lower risk (OR 0.15, 95% CI: 0.018, 0.86, p = 0.045).