MTOR and diabetes mellitus: The phosphoinositide 3‐kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signalling pathway is central to regulating cell transcription, metabolism, survival and inflammation.22, 23 It is well established that during diabetes, defective insulin signalling down‐regulates the activity of PI3K,24 leading to Akt and mTOR inactivation.