Alternately, overexpressed miR‐152‐5p led to strikingly reduced FBXL7 expression in U87 and U251 cells, and significantly enhanced in cells depleted with miR‐152‐5p (Figure 3F), and this relationship was observed in glioma tissues of Grade IV (WHO) (Figure 3G). This evidence concerns the gene FBXL7 and central nervous system cancer.