After comparing the levels of ALT, AST, AFP, and NLR in patients, respectively, we found that HBeAg+ and antiviral therapy had significant effects on ALT levels (P < .0001) (Figure 4A‐C), while cirrhosis, HBeAg+ and antiviral treatment had significant effects on AST, AFP, and NLR (P < .0001) (Figure 4D‐L). The gene discussed is AFP; the disease is Cirrhosis.