The purpose of this study was to investigate if Hyaluronic Acid (HA), TIMP metallopeptidase inhibitor 1 (TIMP1), and Amino-terminal Propeptide of Type III Collagen (PIIINP) alone or combined as an Enhanced Liver Fibrosis (ELF) score, associate with histological liver disease in neonatal baboons exposed to PN with and without intralipids. This evidence concerns the gene TIMP1 and liver disorder.