We previously reported diabetes‐induced up‐regulation of galectin‐1 protein expression mainly in Müller glial cells in the murine retina.10 Consistent with our previous reports,7, 10, 11 galectin‐1/Lgals1 expression in the retina of mice with streptozotocin‐induced diabetes at 2 months was significantly higher than that in controls and was abolished by intravitreal injection of glucocorticoids (Figure 4A,C). Here, LGALS1 is linked to diabetes mellitus.