Furthermore, maternal hypercalcemia caused by FHH1 may potentially cause transient hypoparathyroidism in the unaffected offspring (3), and such hypocalcemia has been reported in 2 unrelated neonates born to mothers with clinically diagnosed FHH (7,8), although the CASR mutation status in these cases was not established. This evidence concerns the gene CASR and hypercalcemia disease.