Anticancer effects and antidepressant mechanisms for glioma have been demonstrated.18, 19 Fluoxetine, the antidepressant of the selective serotonin reuptake inhibitor (SSRI), was demonstrated to reduce NF‐κB activation and sensitize glioblastomas to the chemotherapeutic agent temozolomide (TMZ).20 Fluoxetine also induced apoptosis through the calcium‐mediated intrinsic apoptotic pathway in glioblastoma.19 The gene discussed is NFKB1; the disease is glioblastoma.