Phosphor‐ERK (p‐ERK), the critical kinase activated by Raf/MEK signalling, up‐regulates downstream oncogenic kinases and transcription factor‐mediated tumour cell survival, growth and invasion, resulting in tumour progression.63 The expression of ERR was increased in glioblastoma, and ERK activation was associated with the pathology of glioblastoma. The gene discussed is MAP2K7; the disease is glioblastoma.