In order to explore whether miR-125b-5p was a tumor inhibitor via targeting TRIB2, we divided AMC-HN-8 or M4E cells into four groups, then transfected with miR-NC, miR-125b-5p, miR-125b-5p+vector, or miR-125b-5p+TRIB2, separately. Here, TRIB2 is linked to neoplasm.