CSF1 and adult-onset Still disease: Significantly higher M-CSF levels were observed in AOSD patients with the systemic pattern (median 10.79 pg/mL, IQR 6.40-18.53 pg/mL) compared to those with the chronic articular pattern (6.23 pg/mL, IQR 4.37-8.41 pg/mL) (P = 0.0007) (Figure 3(e)).