GSDMD and breast cancer: Blockade of CD147 with peptide (CD147P, bs-0684P, and BIOSS) in T24 cells, which are malignant BC cell lines, decreased the expression of GSDMD and Ki-67, while overexpression of GSDMD reversed the inhibitory effect of CD147 peptide (CD147P) by Ki-67 expression (Figure 2(c)).