Besides, studies in the past found that the expression of two genes (TNFAIP6 and CTSE) among those was significantly related to pathological features and strongly associated with overall survival [35, 36], suggesting that the selected genes from TCGA and ArrayExpress database based on the algorithm have important clinical value in the promotion of estimating prognosis of bladder cancer. Here, TNFAIP6 is linked to urinary bladder cancer.