Function enrichment analysis showed that GLI2 was involved in Hedgehog signaling pathway, Basal cell carcinoma, Hippo signaling pathway, pathways in cancer, and regulation of transcription, DNA-templated (GO:0006355); ARID3A was enriched in transcription regulatory region sequence-specific DNA binding (GO:0000976) and RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977); MAGI3 could interact with TNK2 to participate in positive regulation of protein phosphorylation (GO:0001934) and growth factor receptor binding (GO:0070851) (Table 6). The gene discussed is TNK2; the disease is cancer.