SEZ6L2 and neoplasm: Additionally, multivariable Cox proportional-hazard results showed that tumor size (HR, 0.461; 95% CI 0.235–0.905; P = 0.024), AFP (HR, 2.262; 95% CI 1.176–4.349; P = 0.014), and high SEZ6L2 expression (HR, 2.499; 95% CI 1.276–4.893; P = 0.008) were independent prognostic factors for OS (Table 2), while tumor size (HR, 0.435; 95% CI 0.221–0.855; P = 0.016), AFP (HR, 2.356; 95% CI 1.237–4.488; P = 0.009), and high SEZ6L2 expression (HR, 2.691; 95% CI 1.371–5.282; P = 0.004) were independent prognostic factors for DFS (Table 3).