Th17 lymphocytes, which are detected in malignant tumors, are characterized by increased expression of CXCR4 and CCR6 receptors, respectively, for the chemokine (C-X-C motif) ligand-12; CXCL12 (SDF-1α) and chemokine (C-C motif) ligand 20 (CCL20) [26]. This evidence concerns the gene CXCL12 and cancer.