In contrast, incubation of CD4+ T cells with IVIg prior to coculture with DCs did not increase the expression of Tregs or CTLA-4+ Tregs (Figures 4(c) and 4(d)), suggesting that IVIg-induced expansion of Tregs and CTLA-4+ Tregs in MG patients through modulation on DCs and the ability of DCs to induce Tregs and CTLA-4+ Tregs is not altered in MG patients. The gene discussed is CD4; the disease is myasthenia gravis.