HOXA4 and cancer: This observation implies that HOXA4 has a specific molecular function and may be important for the maintenance of homeostasis in YAP‐activating conditions, such as cancer 18 or vascular remodeling 3, because repression of the YAP‐TEAD interaction by HOXA4 was only observed with high YAP activity (i.e., low cell density) (Fig 4A).