IGF1 and breast cancer: Although no associations were found between BC risk and IGF‐1 gene rs2195239 polymorphism in a Chinese study, they indicated that this SNP influenced on IGF‐I activity in local tissues of BC.21 They also suggested that another SNP of IGF‐I gene (rs7965399) was associated with the risk of BC.21 Two studies from Japan and America investigated IGF‐1 gene rs2195239 polymorphism in pancreatic cancer, but with inconsistent findings.